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Use of FFPE-derived DNA in next generation sequencing: DNA extraction methods

Archival tissues represent a rich resource for clinical genomic studies, particularly when coupled with comprehensive medical records. Use of these in next generation sequencing (NGS) is a priority. Nine formalin-fixed paraffin-embedded (FFPE) DNA extraction methods were evaluated using twelve FFPE...

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Detalles Bibliográficos
Autores principales: McDonough, Samantha J., Bhagwate, Aditya, Sun, Zhifu, Wang, Chen, Zschunke, Michael, Gorman, Joshua A., Kopp, Karla J., Cunningham, Julie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459541/
https://www.ncbi.nlm.nih.gov/pubmed/30973937
http://dx.doi.org/10.1371/journal.pone.0211400