Quantitative mapping of DNA phosphorothioatome reveals phosphorothioate heterogeneity of low modification frequency

Phosphorothioate (PT) modifications of the DNA backbone, widespread in prokaryotes, are first identified in bacterial enteropathogens Escherichia coli B7A more than a decade ago. However, methods for high resolution mapping of PT modification level are still lacking. Here, we developed the PT-IC-seq...

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Detalles Bibliográficos
Autores principales: Li, Jinli, Chen, Yi, Zheng, Tao, Kong, Lingxin, Zhu, Sucheng, Sun, Yihua, Deng, Zixin, Yang, Litao, You, Delin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459556/
https://www.ncbi.nlm.nih.gov/pubmed/30933976
http://dx.doi.org/10.1371/journal.pgen.1008026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459556/
https://www.ncbi.nlm.nih.gov/pubmed/30933976
http://dx.doi.org/10.1371/journal.pgen.1008026

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