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Inferring rates of metastatic dissemination using stochastic network models

The formation of metastases is driven by the ability of cancer cells to disseminate from the site of the primary tumour to target organs. The process of dissemination is constrained by anatomical features such as the flow of blood and lymph in the circulatory system. We exploit this fact in a stocha...

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Detalles Bibliográficos
Autores principales: Gerlee, Philip, Johansson, Mia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459558/
https://www.ncbi.nlm.nih.gov/pubmed/30933969
http://dx.doi.org/10.1371/journal.pcbi.1006868