Mutational pathway maps and founder effects define the within-host spectrum of hepatitis C virus mutants resistant to drugs

Knowledge of the within-host frequencies of resistance-associated amino acid variants (RAVs) is important to the identification of optimal drug combinations for the treatment of hepatitis C virus (HCV) infection. Multiple RAVs may exist in infected individuals, often below detection limits, at any r...

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Detalles Bibliográficos
Autores principales: Raja, Rubesh, Pareek, Aditya, Newar, Kapil, Dixit, Narendra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459561/
https://www.ncbi.nlm.nih.gov/pubmed/30934020
http://dx.doi.org/10.1371/journal.ppat.1007701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459561/
https://www.ncbi.nlm.nih.gov/pubmed/30934020
http://dx.doi.org/10.1371/journal.ppat.1007701

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