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Mutational pathway maps and founder effects define the within-host spectrum of hepatitis C virus mutants resistant to drugs
Knowledge of the within-host frequencies of resistance-associated amino acid variants (RAVs) is important to the identification of optimal drug combinations for the treatment of hepatitis C virus (HCV) infection. Multiple RAVs may exist in infected individuals, often below detection limits, at any r...
Autores principales: | Raja, Rubesh, Pareek, Aditya, Newar, Kapil, Dixit, Narendra M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459561/ https://www.ncbi.nlm.nih.gov/pubmed/30934020 http://dx.doi.org/10.1371/journal.ppat.1007701 |
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