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Targeting RalGAPα1 in skeletal muscle to simultaneously improve postprandial glucose and lipid control

How insulin stimulates postprandial uptake of glucose and long-chain fatty acids (LCFAs) into skeletal muscle and the mechanisms by which these events are dampened in diet-induced obesity are incompletely understood. Here, we show that RalGAPα1 is a critical regulator of muscle insulin action and go...

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Detalles Bibliográficos
Autores principales: Chen, Qiaoli, Rong, Ping, Zhu, Sangsang, Yang, Xinyu, Ouyang, Qian, Wang, Hong Yu, Chen, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459767/
https://www.ncbi.nlm.nih.gov/pubmed/30989113
http://dx.doi.org/10.1126/sciadv.aav4116