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Targeting RalGAPα1 in skeletal muscle to simultaneously improve postprandial glucose and lipid control
How insulin stimulates postprandial uptake of glucose and long-chain fatty acids (LCFAs) into skeletal muscle and the mechanisms by which these events are dampened in diet-induced obesity are incompletely understood. Here, we show that RalGAPα1 is a critical regulator of muscle insulin action and go...
Autores principales: | Chen, Qiaoli, Rong, Ping, Zhu, Sangsang, Yang, Xinyu, Ouyang, Qian, Wang, Hong Yu, Chen, Shuai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459767/ https://www.ncbi.nlm.nih.gov/pubmed/30989113 http://dx.doi.org/10.1126/sciadv.aav4116 |
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