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Higher levels of B‐cell mutation in the early germinal centres of an inefficient secondary antibody response to a variant influenza haemagglutinin
Designing improved vaccines against mutable viruses such as dengue and influenza would be helped by a better understanding of how the B‐cell memory compartment responds to variant antigens. Towards this we have recently shown, after secondary immunization of mice with a widely variant dengue virus e...
Autores principales: | Tennant, Richard K., Holzer, Barbara, Love, John, Tchilian, Elma, White, Harry N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459774/ https://www.ncbi.nlm.nih.gov/pubmed/30768794 http://dx.doi.org/10.1111/imm.13052 |
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