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Parsimonious Gene Correlation Network Analysis (PGCNA): a tool to define modular gene co-expression for refined molecular stratification in cancer

Cancers converge onto shared patterns that arise from constraints placed by the biology of the originating cell lineage and microenvironment on programs driven by oncogenic events. Here we define consistent expression modules reflecting this structure in colon and breast cancer by exploiting express...

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Detalles Bibliográficos
Autores principales: Care, Matthew A., Westhead, David R., Tooze, Reuben M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459838/
https://www.ncbi.nlm.nih.gov/pubmed/30993001
http://dx.doi.org/10.1038/s41540-019-0090-7