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Defining the genetic and evolutionary architecture of alternative splicing in response to infection

Host and environmental factors contribute to variation in human immune responses, yet the genetic and evolutionary drivers of alternative splicing in response to infection remain largely uncharacterised. Leveraging 970 RNA-sequencing profiles of resting and stimulated monocytes from 200 individuals...

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Detalles Bibliográficos
Autores principales: Rotival, Maxime, Quach, Hélène, Quintana-Murci, Lluis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459842/
https://www.ncbi.nlm.nih.gov/pubmed/30975994
http://dx.doi.org/10.1038/s41467-019-09689-7