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Defining the genetic and evolutionary architecture of alternative splicing in response to infection
Host and environmental factors contribute to variation in human immune responses, yet the genetic and evolutionary drivers of alternative splicing in response to infection remain largely uncharacterised. Leveraging 970 RNA-sequencing profiles of resting and stimulated monocytes from 200 individuals...
Autores principales: | Rotival, Maxime, Quach, Hélène, Quintana-Murci, Lluis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459842/ https://www.ncbi.nlm.nih.gov/pubmed/30975994 http://dx.doi.org/10.1038/s41467-019-09689-7 |
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