Accurate target identification for Mycobacterium tuberculosis endoribonuclease toxins requires expression in their native host

The Mycobacterium tuberculosis genome harbors an unusually high number of toxin-antitoxin (TA) systems. These TA systems have been implicated in establishing the nonreplicating persistent state of this pathogen during latent tuberculosis infection. More than half of the M. tuberculosis TA systems be...

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Detalles Bibliográficos
Autores principales: Cintrón, Melvilí, Zeng, Ju-Mei, Barth, Valdir C., Cruz, Jonathan W., Husson, Robert N., Woychik, Nancy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459853/
https://www.ncbi.nlm.nih.gov/pubmed/30976025
http://dx.doi.org/10.1038/s41598-019-41548-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459853/
https://www.ncbi.nlm.nih.gov/pubmed/30976025
http://dx.doi.org/10.1038/s41598-019-41548-9

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