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Accurate target identification for Mycobacterium tuberculosis endoribonuclease toxins requires expression in their native host
The Mycobacterium tuberculosis genome harbors an unusually high number of toxin-antitoxin (TA) systems. These TA systems have been implicated in establishing the nonreplicating persistent state of this pathogen during latent tuberculosis infection. More than half of the M. tuberculosis TA systems be...
Autores principales: | Cintrón, Melvilí, Zeng, Ju-Mei, Barth, Valdir C., Cruz, Jonathan W., Husson, Robert N., Woychik, Nancy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459853/ https://www.ncbi.nlm.nih.gov/pubmed/30976025 http://dx.doi.org/10.1038/s41598-019-41548-9 |
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