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Small-Molecule Ferroptotic Agents with Potential to Selectively Target Cancer Stem Cells

Effective management of advanced cancer requires systemic treatment including small molecules that target unique features of aggressive tumor cells. At the same time, tumors are heterogeneous and current evidence suggests that a subpopulation of tumor cells, called tumor initiating or cancer stem ce...

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Detalles Bibliográficos
Autores principales: Taylor, William R., Fedorka, Sara R., Gad, Ibtissam, Shah, Ronit, Alqahtani, Hanan D., Koranne, Radhika, Kuganesan, Nishanth, Dlamini, Samkeliso, Rogers, Tim, Al-Hamashi, Ayad, Kholodovych, Veronika, Barudi, Yusuf, Junk, Damian, Rashid, Maisha S., Jackson, Mark W., Tillekeratne, L. M. Viranga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459861/
https://www.ncbi.nlm.nih.gov/pubmed/30976078
http://dx.doi.org/10.1038/s41598-019-42251-5