STING agonists activate latently infected cells and enhance SIV-specific responses ex vivo in naturally SIV controlled cynomolgus macaques

To achieve a functional cure for HIV, treatment regimens that eradicate latently HIV-infected cells must be established. For this, many groups have attempted to reactivate latently-infected cells to induce cytopathic effects and/or elicit cytotoxic T lymphocyte (CTL)/NK cell-mediated immune response...

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Detalles Bibliográficos
Autores principales: Yamamoto, Takuya, Kanuma, Tomohiro, Takahama, Shokichi, Okamura, Tomotaka, Moriishi, Eiko, Ishii, Ken J., Terahara, Kazutaka, Yasutomi, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459902/
https://www.ncbi.nlm.nih.gov/pubmed/30976083
http://dx.doi.org/10.1038/s41598-019-42253-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459902/
https://www.ncbi.nlm.nih.gov/pubmed/30976083
http://dx.doi.org/10.1038/s41598-019-42253-3

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