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Comparative RNA sequencing reveals that HPV16 E6 abrogates the effect of E6*I on ROS metabolism

High-risk Human Papillomavirus infections are responsible for anogenital and oropharyngeal cancers. Alternative splicing is an important mechanism controlling HPV16 gene expression. Modulation in the splice pattern leads to polycistronic HPV16 early transcripts encoding a full length E6 oncoprotein...

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Detalles Bibliográficos
Autores principales: Paget-Bailly, Philippe, Meznad, Koceila, Bruyère, Diane, Perrard, Jérôme, Herfs, Michael, Jung, Alain C., Mougin, Christiane, Prétet, Jean-Luc, Baguet, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459911/
https://www.ncbi.nlm.nih.gov/pubmed/30976051
http://dx.doi.org/10.1038/s41598-019-42393-6