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The secreted Ly6/uPAR-related protein-1 suppresses neutrophil binding, chemotaxis, and transmigration through human umbilical vein endothelial cells

The secreted Ly-6/uPAR Related Protein-1 (SLURP1) is an immunomodulatory protein that promotes corneal immune- and angiogenic-privilege. Here, we have examined the influence of SLURP1 on neutrophil-vascular endothelial cell interactions using human umbilical vein endothelial cells (HUVEC) and differ...

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Detalles Bibliográficos
Autores principales: Swamynathan, Sudha, Tiwari, Anil, Loughner, Chelsea L., Gnalian, John, Alexander, Nicholas, Jhanji, Vishal, Swamynathan, Shivalingappa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459912/
https://www.ncbi.nlm.nih.gov/pubmed/30976100
http://dx.doi.org/10.1038/s41598-019-42437-x