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The mevalonate coordinates energy input and cell proliferation

The mevalonate pathway is known for the synthesis of cholesterol, but recent studies have reported that it also controls Hippo signaling, which is critical for the regulation of organ size and tumorigenesis. Here, we discover that the suppression of the mevalonate pathway inhibits the growth and pro...

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Detalles Bibliográficos
Autores principales: Gong, Li, Xiao, Yi, Xia, Fan, Wu, Pei, Zhao, Tingting, Xie, Shulin, Wang, Ran, Wen, Qiaocheng, Zhou, Wensu, Xu, Huilan, Zhu, Lingyan, Zheng, Zeqi, Yang, Tianlun, Chen, Zihua, Duan, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459916/
https://www.ncbi.nlm.nih.gov/pubmed/30975976
http://dx.doi.org/10.1038/s41419-019-1544-y