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Signal-induced PARP1-Erk synergism mediates IEG expression
A recently disclosed Erk-induced PARP1 activation mediates the expression of immediate early genes (IEG) in response to a variety of extra- and intra-cellular signals implicated in memory acquisition, development and proliferation. Here, we review this mechanism, which is initiated by stimulation-in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459926/ https://www.ncbi.nlm.nih.gov/pubmed/30993015 http://dx.doi.org/10.1038/s41392-019-0042-0 |