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Signal-induced PARP1-Erk synergism mediates IEG expression

A recently disclosed Erk-induced PARP1 activation mediates the expression of immediate early genes (IEG) in response to a variety of extra- and intra-cellular signals implicated in memory acquisition, development and proliferation. Here, we review this mechanism, which is initiated by stimulation-in...

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Detalles Bibliográficos
Autores principales:	Cohen-Armon, Malka, Yeheskel, Adva, Pascal, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459926/ https://www.ncbi.nlm.nih.gov/pubmed/30993015 http://dx.doi.org/10.1038/s41392-019-0042-0

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