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Immobilization of proteolytic enzymes on replica-molded thiol-ene micropillar reactors via thiol-gold interaction

We introduce rapid replica molding of ordered, high-aspect-ratio, thiol-ene micropillar arrays for implementation of microfluidic immobilized enzyme reactors (IMERs). By exploiting the abundance of free surface thiols of off-stoichiometric thiol-ene compositions, we were able to functionalize the na...

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Detalles Bibliográficos
Autores principales: Tähkä, Sari, Sarfraz, Jawad, Urvas, Lauri, Provenzani, Riccardo, Wiedmer, Susanne K., Peltonen, Jouko, Jokinen, Ville, Sikanen, Tiina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459972/
https://www.ncbi.nlm.nih.gov/pubmed/30899997
http://dx.doi.org/10.1007/s00216-019-01674-9