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Development of a hybrid CFD-PBPK model to predict the transport of xenon gas around a human respiratory system to systemic regions

Administering incorrect doses of conventional anesthetic agents through the pulmonary route can cause potential health risks such as blood coagulation, platelet dysfunction, and deteriorating organ function. As an alternative, xenon can minimize the impact on the cardiovascular system and provide th...

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Detalles Bibliográficos
Autores principales: Haghnegahdar, Ahmadreza, Zhao, Jianan, Kozak, Max, Williamson, Patrick, Feng, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460377/
https://www.ncbi.nlm.nih.gov/pubmed/31011641
http://dx.doi.org/10.1016/j.heliyon.2019.e01461