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Development of a hybrid CFD-PBPK model to predict the transport of xenon gas around a human respiratory system to systemic regions
Administering incorrect doses of conventional anesthetic agents through the pulmonary route can cause potential health risks such as blood coagulation, platelet dysfunction, and deteriorating organ function. As an alternative, xenon can minimize the impact on the cardiovascular system and provide th...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460377/ https://www.ncbi.nlm.nih.gov/pubmed/31011641 http://dx.doi.org/10.1016/j.heliyon.2019.e01461 |