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In silico study of 4-phosphorylated derivatives of 1,3-oxazole as inhibitors of Candida albicans fructose-1,6-bisphosphate aldolase II

In this study, the synthesis, in vitro anti-Candida activity and molecular modeling of 4-phosphorylated derivatives of 1,3-oxazole as inhibitors of Candida albicans fructose-1,6-bisphosphate aldolase (FBA-II) are demonstrated and discussed. Significant similarity of the primary and secondary structu...

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Detalles Bibliográficos
Autores principales: Semenyuta, Ivan V., Kobzar, Oleksandr L., Hodyna, Diana M., Brovarets, Volodymyr S., Metelytsia, Larysa O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460381/
https://www.ncbi.nlm.nih.gov/pubmed/31011642
http://dx.doi.org/10.1016/j.heliyon.2019.e01462