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Human dendritic cell-specific ICAM-3-grabbing non-integrin downstream signaling alleviates renal fibrosis via Raf-1 activation in systemic candidiasis

We generated a human dendritic cell-specific ICAM-3-grabbing non-integrin (DC-SIGN) transgenic mouse in which renal tubular epithelial cells expressed DC-SIGN. The transgenic mice were infected with Candida albicans intravenously to study how DC-SIGN expression affected the pathogenesis of systemic...

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Detalles Bibliográficos
Autores principales: Chen, Wen-Yu, Wu, Sheng-Yang, Lin, Ta-Chun, Lin, Shuei-Liong, Wu-Hsieh, Betty A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460490/
https://www.ncbi.nlm.nih.gov/pubmed/30127380
http://dx.doi.org/10.1038/s41423-018-0161-5