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Human dendritic cell-specific ICAM-3-grabbing non-integrin downstream signaling alleviates renal fibrosis via Raf-1 activation in systemic candidiasis
We generated a human dendritic cell-specific ICAM-3-grabbing non-integrin (DC-SIGN) transgenic mouse in which renal tubular epithelial cells expressed DC-SIGN. The transgenic mice were infected with Candida albicans intravenously to study how DC-SIGN expression affected the pathogenesis of systemic...
Autores principales: | Chen, Wen-Yu, Wu, Sheng-Yang, Lin, Ta-Chun, Lin, Shuei-Liong, Wu-Hsieh, Betty A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460490/ https://www.ncbi.nlm.nih.gov/pubmed/30127380 http://dx.doi.org/10.1038/s41423-018-0161-5 |
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