STING palmitoylation as a therapeutic target

Gain-of-function mutations in the STING-encoding gene TMEM173 are central to the pathology of the autoinflammatory disorder STING-associated vasculopathy with onset in infancy (SAVI). Furthermore, excessive activity of the STING signaling pathway is associated with autoinflammatory diseases, includi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hansen, Anne Louise, Mukai, Kojiro, Schopfer, Francisco J., Taguchi, Tomohiko, Holm, Christian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460494/
https://www.ncbi.nlm.nih.gov/pubmed/30796349
http://dx.doi.org/10.1038/s41423-019-0205-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460494/
https://www.ncbi.nlm.nih.gov/pubmed/30796349
http://dx.doi.org/10.1038/s41423-019-0205-5

Ejemplares similares