Skewed X-inactivation is common in the general female population

X-inactivation is a well-established dosage compensation mechanism ensuring that X-chromosomal genes are expressed at comparable levels in males and females. Skewed X-inactivation is often explained by negative selection of one of the alleles. We demonstrate that imbalanced expression of the paterna...

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Detalles Bibliográficos
Autores principales: Shvetsova, Ekaterina, Sofronova, Alina, Monajemi, Ramin, Gagalova, Kristina, Draisma, Harmen H. M., White, Stefan J., Santen, Gijs W. E., Chuva de Sousa Lopes, Susana M., Heijmans, Bastiaan T., van Meurs, Joyce, Jansen, Rick, Franke, Lude, Kiełbasa, Szymon M., den Dunnen, Johan T., ‘t Hoen, Peter A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460563/
https://www.ncbi.nlm.nih.gov/pubmed/30552425
http://dx.doi.org/10.1038/s41431-018-0291-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460563/
https://www.ncbi.nlm.nih.gov/pubmed/30552425
http://dx.doi.org/10.1038/s41431-018-0291-3

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