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Effect of alteplase on platelet function and receptor expression

OBJECTIVE: To investigate the role of alteplase, a widely-used thrombolytic drug, in platelet function. METHODS: Human platelets were incubated with different concentrations of alteplase followed by analysis of platelet aggregation in response to adenosine diphosphate (ADP), collagen, ristocetin, ar...

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Detalles Bibliográficos
Autores principales: Lu, Jun, Hu, Peng, Wei, Guangyu, Luo, Qi, Qiao, Jianlin, Geng, Deqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460619/
https://www.ncbi.nlm.nih.gov/pubmed/30799665
http://dx.doi.org/10.1177/0300060519829991