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Paris polyphylla 26 triggers G2/M phase arrest and induces apoptosis in HepG2 cells via inhibition of the Akt signaling pathway

OBJECTIVES: Paris polyphylla 26 (PP-26) is a monomer purified from Paris polyphylla, which has traditionally been used as an antimicrobial, hemostatic, and anticancer agent in China. The anti-proliferation effect and underlying molecular mechanism of PP-26 were investigated in vitro. METHODS: The ef...

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Detalles Bibliográficos
Autores principales: Li, Qiang, He, Zifan, Liu, Jiming, Wu, Jianlong, Tan, Guixiang, Jiang, Jianwei, Su, Zexuan, Cao, Mingrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460622/
https://www.ncbi.nlm.nih.gov/pubmed/30819018
http://dx.doi.org/10.1177/0300060519826823