PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation

Breakdown of the blood-brain barrier (BBB) and increased immune cell trafficking into the central nervous system (CNS) are hallmarks of the pathogenesis of multiple sclerosis (MS). Platelet endothelial cell adhesion molecule-1 (PECAM-1; CD31) is expressed on cells of the vascular compartment and reg...

Descripción completa

Detalles Bibliográficos
Autores principales: Wimmer, Isabella, Tietz, Silvia, Nishihara, Hideaki, Deutsch, Urban, Sallusto, Federica, Gosselet, Fabien, Lyck, Ruth, Muller, William A., Lassmann, Hans, Engelhardt, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460670/
https://www.ncbi.nlm.nih.gov/pubmed/31024547
http://dx.doi.org/10.3389/fimmu.2019.00711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460670/
https://www.ncbi.nlm.nih.gov/pubmed/31024547
http://dx.doi.org/10.3389/fimmu.2019.00711

Ejemplares similares