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PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation

Breakdown of the blood-brain barrier (BBB) and increased immune cell trafficking into the central nervous system (CNS) are hallmarks of the pathogenesis of multiple sclerosis (MS). Platelet endothelial cell adhesion molecule-1 (PECAM-1; CD31) is expressed on cells of the vascular compartment and reg...

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Detalles Bibliográficos
Autores principales:	Wimmer, Isabella, Tietz, Silvia, Nishihara, Hideaki, Deutsch, Urban, Sallusto, Federica, Gosselet, Fabien, Lyck, Ruth, Muller, William A., Lassmann, Hans, Engelhardt, Britta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460670/ https://www.ncbi.nlm.nih.gov/pubmed/31024547 http://dx.doi.org/10.3389/fimmu.2019.00711

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