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Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk

Epidermal infiltration of neutrophils is a hallmark of psoriasis, where their activation leads to release of neutrophil extracellular traps (NETs). The contribution of NETs to psoriasis pathogenesis has been unclear, but here we demonstrate that NETs drive inflammatory responses in skin through acti...

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Detalles Bibliográficos
Autores principales: Shao, Shuai, Fang, Hui, Dang, Erle, Xue, Ke, Zhang, Jieyu, Li, Bing, Qiao, Hongjiang, Cao, Tianyu, Zhuang, Yuchen, Shen, Shengxian, Zhang, Tongmei, Qiao, Pei, Li, Caixia, Gudjonsson, Johann E., Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460719/
https://www.ncbi.nlm.nih.gov/pubmed/31024570
http://dx.doi.org/10.3389/fimmu.2019.00746