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Targeting the Immunomodulatory CD73/Adenosine System to Improve the Therapeutic Gain of Radiotherapy

Extracellular adenosine is a potent endogenous immunosuppressive mediator critical to the maintenance of homeostasis in various normal tissues including the lung. Adenosine is either released from stressed or injured cells or generated from extracellular adenine nucleotides by the concerted action o...

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Detalles Bibliográficos
Autores principales: de Leve, Simone, Wirsdörfer, Florian, Jendrossek, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460721/
https://www.ncbi.nlm.nih.gov/pubmed/31024543
http://dx.doi.org/10.3389/fimmu.2019.00698