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A general approach to risk modeling using partial surrogate markers with application to perioperative acute kidney injury

BACKGROUND: Surrogate outcomes are often utilized when disease outcomes are difficult to directly measure. When a biological threshold effect exists, surrogate outcomes may only represent disease in specific subpopulations. We refer to these outcomes as “partial surrogate outcomes.” We hypothesized...

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Detalles Bibliográficos
Autores principales: Smith, Derek K., Smith, Loren E., Billings, Frederic T., Blume, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460789/
https://www.ncbi.nlm.nih.gov/pubmed/31093550
http://dx.doi.org/10.1186/s41512-017-0022-1