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Using ordinal outcomes to construct and select biomarker combinations for single-level prediction

BACKGROUND: Biomarker studies may involve an ordinal outcome, such as no, mild, or severe disease. There is often interest in predicting one particular level of the outcome due to its clinical significance. METHODS: A simple approach to constructing biomarker combinations in this context involves di...

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Detalles Bibliográficos
Autores principales: Meisner, Allison, Parikh, Chirag R., Kerr, Kathleen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460803/
https://www.ncbi.nlm.nih.gov/pubmed/31093558
http://dx.doi.org/10.1186/s41512-018-0028-3