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Silica nanoparticles trigger the vascular endothelial dysfunction and prethrombotic state via miR-451 directly regulating the IL6R signaling pathway

BACKGROUND: Safety evaluation is a prerequisite for nanomaterials in a wide range of fields, including chemical industries, medicine or food sciences. Previously, we had demonstrated that SiNPs could trigger the thrombotic effects in vivo, but the underlying mechanisms remain unknown. This study was...

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Detalles Bibliográficos
Autores principales: Feng, Lin, Yang, Xiaozhe, Liang, Shuang, Xu, Qing, Miller, Mark R., Duan, Junchao, Sun, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460825/
https://www.ncbi.nlm.nih.gov/pubmed/30975181
http://dx.doi.org/10.1186/s12989-019-0300-x