PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway

BACKGROUND: The homeodomain transcription factor, PITX2 is associated with tumorigenesis of multiple cancers. In this research, we aimed to study the expression, function and mechanism of PITX2 in lung adenocarcinoma (LUAD). METHODS: The TCGA dataset was used to analyze the expression and clinical s...

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Detalles Bibliográficos
Autores principales: Luo, Jing, Yao, Yu, Ji, Saiguang, Sun, Qi, Xu, Yang, Liu, Kaichao, Diao, Qiang, Qiang, Yong, Shen, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460850/
https://www.ncbi.nlm.nih.gov/pubmed/31043858
http://dx.doi.org/10.1186/s12935-019-0800-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460850/
https://www.ncbi.nlm.nih.gov/pubmed/31043858
http://dx.doi.org/10.1186/s12935-019-0800-7

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