Cargando…

PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway

BACKGROUND: The homeodomain transcription factor, PITX2 is associated with tumorigenesis of multiple cancers. In this research, we aimed to study the expression, function and mechanism of PITX2 in lung adenocarcinoma (LUAD). METHODS: The TCGA dataset was used to analyze the expression and clinical s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Jing, Yao, Yu, Ji, Saiguang, Sun, Qi, Xu, Yang, Liu, Kaichao, Diao, Qiang, Qiang, Yong, Shen, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460850/ https://www.ncbi.nlm.nih.gov/pubmed/31043858 http://dx.doi.org/10.1186/s12935-019-0800-7

Ejemplares similares

FOXH1 promotes lung cancer progression by activating the Wnt/β-catenin signaling pathway
por: Zhang, Jun, et al.
Publicado: (2021)

PITX2 in pancreatic stellate cells promotes EMT in pancreatic cancer cells via the Wnt/β-catenin pathway: PITX2 promotes pancreatic cancer progression via Wnt/β-catenin pathway
por: Wu, Di, et al.
Publicado: (2023)

LncRNA CBR3-AS1 potentiates Wnt/β-catenin signaling to regulate lung adenocarcinoma cells proliferation, migration and invasion
por: Hou, Min, et al.
Publicado: (2021)

Oncogenic UBE3C promotes breast cancer progression by activating Wnt/β-catenin signaling
por: Hang, Chen, et al.
Publicado: (2021)

PlGF knockdown attenuates hypoxia-induced stimulation of cell proliferation and glycolysis of lung adenocarcinoma through inhibiting Wnt/β-catenin pathway
por: Zhang, Wei, et al.
Publicado: (2021)

UBQLN4 promotes progression of HCC via activating wnt-β-catenin pathway and is regulated by miR-370
por: Yu, Yan, et al.
Publicado: (2020)

Tre2 (USP6NL) promotes colorectal cancer cell proliferation via Wnt/β-catenin pathway
por: Sun, Kang, et al.
Publicado: (2019)

ERBB3 binding protein 1 promotes the progression of malignant melanoma through activation of the Wnt/ β-catenin signaling pathway
por: Bao, Yanqiu, et al.
Publicado: (2022)

CD44 targets Wnt/β-catenin pathway to mediate the proliferation of K562 cells
por: Chang, Guoqiang, et al.
Publicado: (2013)

Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer
por: Wei, Jinlai, et al.
Publicado: (2022)

CCR9 initiates epithelial–mesenchymal transition by activating Wnt/β-catenin pathways to promote osteosarcoma metastasis
por: Kong, Haoran, et al.
Publicado: (2021)

TRIP6 enhances stemness property of breast cancer cells through activation of Wnt/β-catenin
por: Zhao, Xiaohui, et al.
Publicado: (2020)

LncRNA LEF1-AS1 promotes metastasis of prostatic carcinoma via the Wnt/β-catenin pathway
por: Li, Weiyuan, et al.
Publicado: (2020)

Activating transcription factor 5 (ATF5) promotes tumorigenic capability and activates the Wnt/b-catenin pathway in bladder cancer
por: Zhou, Junhao, et al.
Publicado: (2021)

Knockdown of AGGF1 inhibits the invasion and migration of gastric cancer via epithelial–mesenchymal transition through Wnt/β-catenin pathway
por: Yao, Han-Hui, et al.
Publicado: (2019)

Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway
por: Liu, Qian-Qian, et al.
Publicado: (2016)

TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma
por: Tong, Qing, et al.
Publicado: (2022)

SNHG29 regulates miR-223-3p/CTNND1 axis to promote glioblastoma progression via Wnt/β-catenin signaling pathway
por: Han, Lizhang, et al.
Publicado: (2019)

Loss of DSTYK activates Wnt/β-catenin signaling and glycolysis in lung adenocarcinoma
por: Zhong, Chenxi, et al.
Publicado: (2021)

Long non-coding RNA LINC01314 represses cell migration, invasion, and angiogenesis in gastric cancer via the Wnt/β-catenin signaling pathway by down-regulating KLK4
por: Tang, Lin, et al.
Publicado: (2019)

Dact2 Represses PITX2 Transcriptional Activation and Cell Proliferation through Wnt/beta-Catenin Signaling during Odontogenesis
por: Li, Xiao, et al.
Publicado: (2013)

Long non-coding RNA DANCR promotes cervical cancer growth via activation of the Wnt/β-catenin signaling pathway
por: Tian, Wanjia, et al.
Publicado: (2020)

TACR2 is associated with the immune microenvironment and inhibits migration and proliferation via the Wnt/β-catenin signaling pathway in prostate cancer
por: Jianfeng, Wang, et al.
Publicado: (2021)

NCAPG facilitates colorectal cancer cell proliferation, migration, invasion and epithelial–mesenchymal transition by activating the Wnt/β-catenin signaling pathway
por: Shi, Yanlong, et al.
Publicado: (2022)

MiR-924 as a tumor suppressor inhibits non-small cell lung cancer by inhibiting RHBDD1/Wnt/β-catenin signaling pathway
por: Wang, Huaishi, et al.
Publicado: (2020)

miR-155-5p modulates malignant behaviors of hepatocellular carcinoma by directly targeting CTHRC1 and indirectly regulating GSK-3β-involved Wnt/β-catenin signaling
por: Chen, Gang, et al.
Publicado: (2017)

Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling
por: Lien, Wen-Hui, et al.
Publicado: (2014)

Chromobox 4 facilitates tumorigenesis of lung adenocarcinoma through the Wnt/β-catenin pathway
por: Wang, Zuoyun, et al.
Publicado: (2020)

Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer
por: Bian, Jia, et al.
Publicado: (2020)

Wnt/β-Catenin-Dependent Transcription in Autism Spectrum Disorders
por: Caracci, Mario O., et al.
Publicado: (2021)

The recent progress of peptide regulators for the Wnt/β-catenin signaling pathway
por: Zhang, Nan, et al.
Publicado: (2023)

RNA-binding motif protein 10 represses tumor progression through the Wnt/β- catenin pathway in lung adenocarcinoma
por: Cao, Yingyue, et al.
Publicado: (2022)

GOLPH3 Promotes Angiogenesis of Lung Adenocarcinoma by Regulating the Wnt/β-Catenin Signaling Pathway
por: Zhao, Canjun, et al.
Publicado: (2020)

MicroRNA-665 facilitates cell proliferation and represses apoptosis through modulating Wnt5a/β-Catenin and Caspase-3 signaling pathways by targeting TRIM8 in LUSC
por: Chen, Tian-Jun, et al.
Publicado: (2021)

WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma
por: Arensman, Michael D., et al.
Publicado: (2013)

miR-199b-3p contributes to acquired resistance to cetuximab in colorectal cancer by targeting CRIM1 via Wnt/β-catenin signaling
por: Han, Hu, et al.
Publicado: (2022)

LINC00115 promotes stemness and inhibits apoptosis of ovarian cancer stem cells by upregulating SOX9 and inhibiting the Wnt/β-catenin pathway through competitively binding to microRNA-30a
por: Hou, Rui, et al.
Publicado: (2021)

Long non-coding RNA NORAD contributes to the proliferation, invasion and EMT progression of prostate cancer via the miR-30a-5p/RAB11A/WNT/β-catenin pathway
por: Zhang, Yunxia, et al.
Publicado: (2020)

WNKs in Wnt/β-catenin signaling
por: Serysheva, Ekatherina, et al.
Publicado: (2014)

Wnt/β-Catenin Signaling and Obesity
por: Chen, Na, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_1j9jipho4i6ggm6a31jvh9b924