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Pancreatic Cancer Heterogeneity Can Be Explained Beyond the Genome

Pancreatic ductal adenocarcinoma (PDAC) remains a major health problem because it induces almost systematic mortality. Carcinogenesis begins with genetic aberrations which trigger epigenetic modifications. While genetic mutations initiate tumorigenesis, they are unable to explain the vast heterogene...

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Detalles Bibliográficos
Autores principales: Juiz, Natalia Anahi, Iovanna, Juan, Dusetti, Nelson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460948/
https://www.ncbi.nlm.nih.gov/pubmed/31024848
http://dx.doi.org/10.3389/fonc.2019.00246