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Treadmill Exercise Decreases Aβ Deposition and Counteracts Cognitive Decline in APP/PS1 Mice, Possibly via Hippocampal Microglia Modifications

Recent studies have suggested that exercise may be beneficial for delaying or attenuating Alzheimer’s disease (AD). However, the underlying mechanisms were not clear. Microglia-mediated neuroinflammation is suggested to play an important role in the pathology of AD. The present study investigated th...

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Detalles Bibliográficos
Autores principales: Zhang, Xianliang, He, Qiang, Huang, Tao, Zhao, Na, Liang, Fei, Xu, Bo, Chen, Xianghe, Li, Tuojian, Bi, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461026/
https://www.ncbi.nlm.nih.gov/pubmed/31024293
http://dx.doi.org/10.3389/fnagi.2019.00078