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Role of Src and Cortactin in Pemphigus Skin Blistering

Autoantibodies against desmoglein (Dsg) 1 and Dsg3 primarily cause blister formation in the autoimmune disease pemphigus vulgaris (PV). Src was proposed to contribute to loss of keratinocyte cohesion. However, the role and underlying mechanisms are unclear and were studied here. In keratinocytes, ce...

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Detalles Bibliográficos
Autores principales: Kugelmann, Daniela, Rötzer, Vera, Walter, Elias, Egu, Desalegn Tadesse, Fuchs, Michael Tobias, Vielmuth, Franziska, Vargas-Robles, Hilda, Schnoor, Michael, Hertl, Michael, Eming, Rüdiger, Rottner, Klemens, Schmidt, Ansgar, Spindler, Volker, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461052/
https://www.ncbi.nlm.nih.gov/pubmed/31024527
http://dx.doi.org/10.3389/fimmu.2019.00626