Exosomes from N-Myc amplified neuroblastoma cells induce migration and confer chemoresistance to non-N-Myc amplified cells: implications of intra-tumour heterogeneity

Neuroblastoma accounts for 15% of childhood cancer mortality. Amplification of the oncogene N-Myc is a well-established poor prognostic marker for neuroblastoma. Whilst N-Myc amplification status strongly correlates with higher tumour aggression and resistance to treatment, the role of N-Myc in the...

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Detalles Bibliográficos
Autores principales: Fonseka, Pamali, Liem, Michael, Ozcitti, Cemil, Adda, Christopher G., Ang, Ching-Seng, Mathivanan, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461098/
https://www.ncbi.nlm.nih.gov/pubmed/31007876
http://dx.doi.org/10.1080/20013078.2019.1597614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461098/
https://www.ncbi.nlm.nih.gov/pubmed/31007876
http://dx.doi.org/10.1080/20013078.2019.1597614

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