Mitigating the effects of reference sequence bias in single-multiplex massively parallel sequencing of the mitochondrial DNA control region

Sequence analysis of the mitochondrial DNA (mtDNA) control region can provide forensically useful information, particularly in challenging samples where autosomal DNA profiling fails. Sub-division of the 1122-bp region into shorter PCR fragments improves data recovery, and such fragments can be anal...

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Detalles Bibliográficos
Autores principales: Huszar, Tunde I., Wetton, Jon H., Jobling, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461131/
https://www.ncbi.nlm.nih.gov/pubmed/30682697
http://dx.doi.org/10.1016/j.fsigen.2019.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461131/
https://www.ncbi.nlm.nih.gov/pubmed/30682697
http://dx.doi.org/10.1016/j.fsigen.2019.01.008

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