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Mitigating the effects of reference sequence bias in single-multiplex massively parallel sequencing of the mitochondrial DNA control region
Sequence analysis of the mitochondrial DNA (mtDNA) control region can provide forensically useful information, particularly in challenging samples where autosomal DNA profiling fails. Sub-division of the 1122-bp region into shorter PCR fragments improves data recovery, and such fragments can be anal...
Autores principales: | Huszar, Tunde I., Wetton, Jon H., Jobling, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461131/ https://www.ncbi.nlm.nih.gov/pubmed/30682697 http://dx.doi.org/10.1016/j.fsigen.2019.01.008 |
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