Endothelial cells secreted endothelin-1 augments diabetic nephropathy via inducing extracellular matrix accumulation of mesangial cells in ETBR(-/-) mice

Endothelin B receptor (ETBR) deficiency may contribute to the progression of diabetic nephropathy (DN) in a streptozotocin (STZ) model, but the underlying mechanism is not fully revealed. In this study, STZ-diabetic ETBR(-/-) mice was characterized by increased serum creatinine and urinary albumin,...

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Detalles Bibliográficos
Autores principales: Zou, Hong-hong, Wang, Li, Zheng, Xiao-xu, Xu, Gao-si, Shen, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461170/
https://www.ncbi.nlm.nih.gov/pubmed/30926764
http://dx.doi.org/10.18632/aging.101875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461170/
https://www.ncbi.nlm.nih.gov/pubmed/30926764
http://dx.doi.org/10.18632/aging.101875

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