Cargando…

Ischemic postconditioning prevents surge of presynaptic glutamate release by activating mitochondrial ATP-dependent potassium channels in the mouse hippocampus

A mild ischemic load applied after a lethal ischemic insult reduces the subsequent ischemia–reperfusion injury, and is called ischemic postconditioning (PostC). We studied the effect of ischemic PostC on synaptic glutamate release using a whole-cell patch-clamp technique. We recorded spontaneous exc...

Descripción completa

Detalles Bibliográficos
Autores principales: Yokoyama, Shohei, Nakagawa, Ichiro, Ogawa, Yoichi, Morisaki, Yudai, Motoyama, Yasushi, Park, Young Su, Saito, Yasuhiko, Nakase, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461229/
https://www.ncbi.nlm.nih.gov/pubmed/30978206
http://dx.doi.org/10.1371/journal.pone.0215104