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Ischemic postconditioning prevents surge of presynaptic glutamate release by activating mitochondrial ATP-dependent potassium channels in the mouse hippocampus
A mild ischemic load applied after a lethal ischemic insult reduces the subsequent ischemia–reperfusion injury, and is called ischemic postconditioning (PostC). We studied the effect of ischemic PostC on synaptic glutamate release using a whole-cell patch-clamp technique. We recorded spontaneous exc...
Autores principales: | Yokoyama, Shohei, Nakagawa, Ichiro, Ogawa, Yoichi, Morisaki, Yudai, Motoyama, Yasushi, Park, Young Su, Saito, Yasuhiko, Nakase, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461229/ https://www.ncbi.nlm.nih.gov/pubmed/30978206 http://dx.doi.org/10.1371/journal.pone.0215104 |
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