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Constipation in Tg2576 mice model for Alzheimer’s disease associated with dysregulation of mechanism involving the mAChR signaling pathway and ER stress response

BACKGROUND: Although constipation has been researched in various neurological disorders, including Parkinson’s disease (PD) and spinal cord injury (SCI), the pathological mechanism of this symptom has not been investigated in Alzheimer’s disease (AD) associated with loss of nerve cells in the brain....

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Detalles Bibliográficos
Autores principales: Kim, Ji Eun, Park, Jin Ju, Lee, Mi Rim, Choi, Jun Young, Song, Bo Ram, Park, Ji Won, Kang, Mi Ju, Son, Hong Joo, Hong, Jin Tae, Hwang, Dae Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461235/
https://www.ncbi.nlm.nih.gov/pubmed/30978260
http://dx.doi.org/10.1371/journal.pone.0215205