Targeted disruption of glycogen synthase kinase-3β in cardiomyocytes attenuates cardiac parasympathetic dysfunction in type 1 diabetic Akita mice

Type 1 diabetic Akita mice develop severe cardiac parasympathetic dysfunction that we have previously demonstrated is due at least in part to an abnormality in the response of the end organ to parasympathetic stimulation. Specifically, we had shown that hypoinsulinemia in the diabetic heart results...

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Detalles Bibliográficos
Autores principales: Zhang, Yali, Welzig, Charles M., Haburcak, Marian, Wang, Bo, Aronovitz, Mark, Blanton, Robert M., Park, Ho-Jin, Force, Thomas, Noujaim, Sami, Galper, Jonas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461277/
https://www.ncbi.nlm.nih.gov/pubmed/30978208
http://dx.doi.org/10.1371/journal.pone.0215213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461277/
https://www.ncbi.nlm.nih.gov/pubmed/30978208
http://dx.doi.org/10.1371/journal.pone.0215213

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